Imveliso eluhlaza ye-cannabis kunye neoyile ye-cannabis yeenjongo zonyango.UGuillaume Payen / Imifanekiso ye-SOPA / i-LightRocket nge-Getty Izithombe Apha kuza enye intengiso ye-cannabinoid boom. Ukuba awukayiboni okwangoku, jonga ngeenxa zonke: I-CBG (okanye i-cannabigerol) ngequbuliso kuyo yonke indawo, ifakwe kwioyile, kwimixube, kwiifomsile, intlaka , kwaye kwi intyatyambo epheleleyo yezityalo .
Ngaba iyazifeza izithembiso zayo? Kuxhomekeke ekubeni ubuza kubani. Ubulumko obuqhelekileyo obujikeleze intsangu abuchanekanga, ingxaki yolwazi eyenziwe kukuthintelwa kodwa igcinwe-kwaye ngeendlela ezininzi ikhuthazwa lushishino lwe-cannabis yanamhlanje.
Umhlobo Wenene FM iklasi ikuxelele ukuba i-cannabis inesithako esinye esisebenzayo, i-THC. Emva koko ufumanisa ukuba unamakhulu aliqela. Emva koko kwafika abachaphazeli bempilo entle, ukusuka kuGwyneth Paltrow kunye neGoOP ukuya kwikona yebodega, bekuxelela konke ngomlingo we-CBD-kunye nokupakishwa okubonisa ii-cannabinoids ezisempilweni kwimveliso yokutya kunye nobuhle. I-THC imbi! I-CBD ilungile! yayilifutshane elingelilo elichanekileyo lokuyila abantu abaninzi baseMelika abadidekileyo abashiyekileyo, ngaphandle kobungqina obuncinci kakhulu bamandla e-CBD kwaye I-THC ibonakalise amandla ekupheliseni iintlungu, ukukhuthaza ukutya, kunye nokulwa nomhlaza.
I-CBG ayivavanywanga ngakumbi. Ngokungafaniyo ne-THC, ethintelwe ngumthetho womdibaniso kwaye ilawulwa kakhulu ngurhulumente, ngokungafaniyo ne-CBD, eya isiba ngamapolisa kuLawulo lokutya kunye noLawulo lweziyobisi, akukho mithetho ijikeleze i-CBG okwangoku.
Ngenxa yoko, kukho ukukhula kwenzala ekusetyenzisweni kwezorhwebo kwale phytocannabinoid engalawulwa, njenge UKent Vrana , ugqirha wamayeza ophambili kwiKholeji yasePenn State yoNyango kunye nengcali yee-cannabinoids uyibeke kwinqaku lakutshanje .
Ke yintoni i-CBG, yenza ntoni-kwaye siyazi njani le nto? Okungakumbi ukuya kwinqanaba: Ngaba ufanele uthenge ezinye kwaye uzame ezinye, ngelixa abaphandi kunye neengcali zonyango bezama ukufumanisa konke oku? Kwaye kufuneka wenze ntoni ngemizamo yokuthengisa ye-cannabis okwangoku?
Nangona isaziwa, i-CBG ayisiyonto intsha kwisayensi, kodwa intengiso entsha yentengiso igxininisa ukungazi kwesayensi.
Njengoko uVrana ephawula, iCannabigerol (CBG) okwangoku ithengiswa njengesongezelelo sokutya kwaye, njenge-cannabidiol (CBD) ngaphambili, amabango amaninzi ayenziwa malunga nezibonelelo zawo.
Kodwa, [u] ayifani ne-CBD, nangona kunjalo, uphando oluncinci lwenziwe kule molekyuli ingalawulwayo.
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Ukubandakanyeka kuka-Andrey Kukushkin kwinqanaba eliphezulu nabaphandi abaphambili kurhulumente wobumbano kuphakamisa imibuzo malunga nokuba imali yelinye ilizwe ethululela kwi-cannabis yase-US, kubandakanya nemali evela eMpuma Yurophu, iya phi, iingcali zitsho.Imifanekiso ka-Ethan Miller / Getty
Ukubandakanyeka kuka-Andrey Kukushkin kwinqanaba eliphezulu nabaphandi abaphambili kurhulumente wobumbano kuphakamisa imibuzo malunga nokuba imali yelinye ilizwe ethululela kwi-cannabis yase-US, kubandakanya nemali evela eMpuma Yurophu, iya phi, iingcali zitsho.Kunqabile ukuba kuninzi, kunye nezityalo ze-cannabis ezivunyiweyo ngokubanzi ezenziwe malunga neepesenti ze-1 ze-CBG ngokobunzima, ezibuza imibuzo malunga nokuba iinkampani ze-cannabis zivuna njani ngokwaneleyo okanye zizalisa izityalo ngokwahlukileyo kwiimveliso zentengiso eziqhayisa ngeepesenti ezingama-20 ze-CBG.
Ukwahlukana kolwazi kunye nokunqongophala akubanqandanga oosomashishini ekufuneni imarike yezoqoqosho elandelayo, kwaye kubonakala ngathi ioyile ye-CBG ingangqineka iyile ntengiso, uVrana wabhala-kwaye oku nangona kukho umsantsa wolwazi kwaye abanye bengengomngcipheko ungabalulekanga.
Kukho amava angonelanga kule phytocannabinoid enqabileyo kwaye ukubakho kweziphumo ezibi kuphezulu, wabhala uVrana.
Ukucaca, i-CBG ibonakala ngathi inezonyango ezisemthethweni, zombini zisekwe kwizifundo zamva nje nakwimigaqo yesayensi.
Uphononongo lwamva nje lucebise ukuba i-cannabinoid inokwenyani ezinokubakho njengeyeza lokubulala iintsholongwane . Kuye kwatyhalwa njenge-cannabinoid encinci, kunye amandla kunyango lokunciphisa umzimba kunye nezifo ze-metabolic. Kwaye eneneni, uphononongo lwakutshanje lweziphumo ze-CBG ze-pharmacological zibonakalise amandla azo njengonyango lwe-metabolic syndrome.
Ungayibona i-CBG kuthengisiwe njengomama wazo zonke ii-cannabinoids. Kungenxa yokuba i-cannabinoid yokuqala echongiweyo yesityalo se-cannabis evelisa i-cannabigerolic acid (i-CBGA), ethi ke iguqulwe ibe zizandulela ze-biosynthetic ziye kwi-THC nakwi-CBD. Nangona kunjalo, ngokukodwa, kukho i-CBG encinci kwisityalo sokugqibela.
Ii-cannabinoids ezinje nge-THC kunye ne-CBD zisebenza ngokuzibophelela kwii-receptors ezithile kwinkqubo yeemvakalelo zomntu. Umsebenzi kwezi receptors unceda ukulawula imisebenzi ephambili yomzimba njengemood, umdla wokutya kunye nokulala. Ngokubalulekileyo, nangona i-CBG ibonakala ngathi iziphatha ngokungafaniyo ne-THC kune-CBD kwezinye ii-receptors, i-CBG ikwasebenza kwizamkeli ezahlukeneyo kunaleyo yenziwe yi-THC kunye ne-CBD.
Okona kubaluleke kakhulu, i-CBG ibonakala ngathi inamandla kakhulu kwi-agonist ye-alpha-2 adrenergic receptor. Ukusuka kwimbono yezonyango, oku kokona kubaluleke kakhulu ekufumaneni.
Iziyobisi okanye unyango Ukujolisa kuloo mntu wamkela sele zisetyenziselwa unyango lweengxaki ezininzi, ukusuka ekurhoxisweni kwe-opiate kunye neminqweno yecuba ukuya kwixinzelelo, uxinzelelo, iintlungu kunye ne-ADHD.
Kodwa akukho nanye yale nto yokuba umxube we-CBG okhoyo kwimarike unokulinganisa amayeza amayeza ajolise kulwamkelo. Inyaniso, njenge-CBD , I-CBG inokuba yingxaki xa idityaniswe neziyobisi.
Ukusuka kumandla e-CBG kule receptor ye-adrenergic, ukungenisa kunokutshintsha ngokungalindelekanga uxinzelelo lwegazi, ukuhambisa isisu, kunye nokunxibelelana namanye amayeza eentliziyo, uVrana wabhala.
Kwaye nangona kubonakala ngathi umsebenzi we-alpha-2 luphawu olwaneleyo lokuba i-cannabinoid iya kuba namandla amakhulu kwezonyango, kukho izizathu zokujonga i-CBG yedosi ephezulu yeziphumo ebezingalindelekanga ngaphaya kokunxibelelana neziyobisi. Ukuchasana noxinzelelo lwegazi yi-hypotension, okanye uxinzelelo lwegazi oluphantsi. Imvakalelo yentloko engacacanga okanye ukumnyama ngaphandle okubizwa ngokuba yi-orthostatic hypotension ibhaliwe phakathi kwabasebenzisi be-cannabis-i-CBG ingadlala indima apha?
Kungenzeka, ewe. I-CBG inokusebenzisana namanye amachiza kwaye idale iingxaki ezingalindelekanga okanye iziphumo ezingafunekiyo. Kwaye kukho umbuzo owongezelelweyo wokuba yeyiphi ifuthe i-CBG eya kuba nayo iyodwa okanye xa idityaniswe nezinye ii-cannabinoids.
Konke oku kukuthi kuninzi esingakwaziyo kunokuba sikwazi malunga ne-CBG. Ufuna malini, kwaye ngayiphi injongo? Yonke le mibuzo iya kuphendula ixesha elininzi kunye nophando olungakumbi. Okwangoku, uninzi lweemveliso ze-CBG ziyafumaneka.
Njengoko uVrana ebhala, kukho ukubakho okubonakalayo kwezifo ezithile-kwaye yindlela i-cannabinoid eya kuthengiswa ngayo, ngaphandle kweziphumo ezibonakalayo.
Amandla amakhulu, ulwazi oluncinci lokwenyani, kunye ne-hype enkulu: ngumzi-mveliso we-cannabis, kwaye ngowona mgca uphantsi we-CBG.
