U-Eric Marcotulli, uDan Alminana kunye noLeonard Guarente wezeMpilo e-Elysium.Elysium Impilo Kwiminyaka emithathu edlulileyo, uEric Marcotulli, uDan Alminana kunye noLeonard Guarente basungula Elysium Impilo , inkampani ethe ngqo-kubathengi edibanisa uluntu kwizazinzulu, isika i-clutter ye-pharma enkulu kwifilosofi yasetafileni. Ukujonga inzululwazi ye-Elysium Health isichotho esivela IHarvard kwaye NGE -Kuba ibhodi yabo yeengcebiso iyaqhayisa Sixhengxe I-Nobel Laureates kwi-chemistry kunye ne-physiology-kukho impikiswano ephosakeleyo yokuthembela ukuba i-Basis, imveliso yokuqala yenkampani, ngokwenene iyona yongeza imihla ngemihla iiseli zakho ezifunekayo.
Kodwa ngenxa yokuba ungakholelwa kuyo yonke into oyibonayo kwi-intanethi, nasi esinye isizathu sokuqhubeka nokufunda: Ngelixa idatha yabathengi ka-Elysium ingumnini, ngokukaWhitney Christopher, umlawuli wenkampani yabathengi i-PR, iipesenti ezili-10 zabasebenzisi beBasis ngoogqirha.
Ke, yintoni kanye kanye iSiseko? Ngokuka-ElysiumHealth.com (apho ukuthengiswa kwenyanga enye kuthengiswa nge-60 yeedola): Iiseli zifuna i-coenzyme NAD + ukuba isebenze, kwaye i-NAD + iyancipha njengoko sikhula. Isiseko siqinisekisiwe ukuba sonyusa amanqanaba e-NAD +.
Nanku apho kunika umdla: Ngokungafaniyo uninzi lweevithamini kunye nezongezo zokutya-kubandakanya ukuyibuyisela kwakhona , ethe yathathwa njengechiza lokulwa ukuguga ziinkampani zobuhle iminyaka-iimolekyuli kwi-Basis zibonisiwe ayifumaneki , Oko kuthetha ukuba bangena emzimbeni kwaye benze le nto bajonge kuyo, kubandakanya nokuphakamisa amanqanaba e-NAD +. Kumjikelo wokuqala wenkampani kuvavanyo lweklinikhi, u-Elysium waqhuba isifundo esingaboni kabini apho abathathi-nxaxheba abali-120 phakathi kweminyaka engama-60-80 bohlulwa baba ngamaqela amathathu. Iqela lokuqala lafumana idosi yemihla ngemihla ye-Basis (250 mg ye INicotinamide Riboside kunye ne-50 mg ye Pterostilbene ), Iqela lesibini lafumana idosi ephakanyisiweyo yansuku zonke, kwaye iqela lesithathu lafumana i-placebo. Emva kweeveki ezine kuphela, iimvavanyo zegazi zatyhila ukuba amanqanaba asisiseko eqela lokuqala le-NAD + ayenyuke ngepesenti ye-40-kwaye yagcina olo nyuso lwentsalela yolingo lweeveki ezisibhozo. Abathathi-nxaxheba bathatha iidosi eziphindwe kabini zeBasis babone ukonyuka kwesiseko seepesenti ezingama-90, nazo zigcinekile. 
Imveliso yokuqala ye-Elysium, Isiseko, yakhutshwa kwi-2015.Elysium Impilo
Ngelixa u-Elysium elumke engenzi mabango malunga nezibonelelo zezempilo ze-Basis, i-coenzyme NAD +, iminyaka, ihlonitshwe njengomthombo wolutsha phakathi Uluntu lwe-bio-hacker -Ikakhulu ukukwazi kwayo ukuphucula imetabolism, ukulwa nokuguga kwinqanaba leselula, kunye nokunciphisa ukudinwa. Izifundo zikwabonakalisile ukuba i-NAD + ibalulekile kwisingqisho se-circadian (okt ukulala kamnandi ebusuku). Njengoko Inzululwazi imihla ngemihla uxelwe kwisifundo seYunivesithi yaseNyakatho-ntshona kwi2013:
IMitochondria ilawula unikezelo lwamandla kwiiseli xa siphumle, kungekho glucose ifumaneka ekutyeni. Kuphononongo lweempuku, abaphandi bafumanise ukuba iwotshi ejikelezayo ibonelela ngomdlalo ukukhanyisa isithando somlilo kwaye kwincam yomdlalo yindawo ebalulekileyo ebizwa ngokuba yi-NAD +. Idibanisa ne-enzyme kwi-mitochondria ebizwa ngokuba yi-Sirtuin 3, esebenza njengeqhwitha, ukukhanyisa isithando somlilo. Xa iwotshi yesilwanyana ingasebenzi, isilwanyana asinakho ukuhambisa amandla agciniweyo kwaye inkqubo ayicimi ... Iziphumo zibonisa ukuba iwotshi ejikelezayo, umgcini wexesha wofuzo oguquke wenza ukuba izinto zilandele umkhondo wotshintsho lwemihla ukusuka ekukhanyeni ebumnyameni kwangoko kwindaleko, ivelisa ukungxama kumandla emitochondrial ngokusebenzisa isingqisho somgaqo we-NAD + biosynthesis.
I-NAD + ikwadlala indima ekuvuseleleni iiselula, ethi uJim Manzi, umtyali mali kwinkampani, akhawuleze ayiqinisekise. Ukujonga kwakhona inguqulelo efinyeziweyo yerejista kaManzi yanele ukukhupha umntu oqhelekileyo: Njenge-CEO yeLotus, uMenzi wakhulisa inkampani ukusuka kubasebenzi abali-10 ukuya kuma-4,000 ngaphambi kokuthengisa kwi-IBM nge-3.5 yezigidigidi zeedola, emva koko wajoyina uMcKinsey, watyala imali kwi-FreshDirect (phakathi kwezinto ezininzi. , ezinye izinto ezininzi) kwaye ngoku usebenza njengosihlalo weThermo Fisher, ikhaya labasebenzi abangama-57,000 kwihlabathi liphela. Ekuqaleni kwale veki e IBlue Hill kwi-Stone Barns , UMenzi ukhanyise into yokugqibela ongathanda ukuyibona ekuqaleni kwesidlo sasemini esineekhosi ezintandathu: ifoto yobuso bakhe obabunegazi, idumbile, inenxeba elibi. Amanxeba emfazwe avela entlokweni ebhabha-ngaphezulu ngaphezulu kweentsimbi zakhe ngelixa ehamba ngebhayisikile kweli hlobo eDenmark.
Ndithintele ukonakala kwexesha elide emazinyweni nasemhlathini kodwa bendidinga ukuthungwa kali-10, ucacisile. Ngaphantsi kweeveki ezimbini kamva, kumtshato wentombi yomhlobo wakhe eRoma, ukusikwa kwakhe kwakuphantse kwaphela. Zonke izinto ezixutywayo zilungisiwe ubukhulu becala, ngaphandle kombala ohlukileyo ocacileyo kulusu olutsha olukhule umva. Ndamangaliswa, njengabo bonke abahlobo bam emtshatweni ababone iifoto zengozi. Umfazi wam wayengakholelwa kwisantya sokubuyela kwimeko yesiqhelo. Umfazi kaMenzi, u-Kay Calvert, ungumlawuli wezobuchwephese, kwaye unika isiseko sokuthintela nokuncipha kokutshiswa lilanga kuhambo lwamva nje oluya e-St Bart's (kufundo luka-2009, i-NAD + yaboniswa ukunciphisa ubuntununtunu kwi-photodamage) . Zombini uMenzi kunye noCalvert bathatha iicapsule ezine zeSiseko yonke imihla-iphindwe kabini idosi ekhuthazwayo.
Njengoko I-TechCrunch ixeliwe kuDisemba ophelileyo, u-Elysium ufumene i-20 yezigidi zeedola kwizimali ze-Series B, kulandela ukuxabisa i-157 yezigidi zeedola. Ngokwiphepha lomsebenzi lenkampani, u-Elysium uceba ukuphindaphindeka kane ngobukhulu, ekhula esuka kwi-25 ukuya kwi-100 + kubasebenzi kwiinyanga ezingama-24 ezizayo.
