Kwisithuba nje esingaphezulu kwenyanga eyadlulayo, umfana wazifumana sele ekwinkqubo yokungalali kakuhle. Emva kobusuku kunye neqela labahlobo-isidlo sangokuhlwa kwi-Lower East Side, iziselo eSoo House-wazifumana eyedwa kwikhaya lomhleli ophezulu kwimagazini eyaziwayo yefashoni. Oku akuzange kubonakale kuyinto embi: Eli bhinqa lalikwiminyaka yama-30 ubudala, linomtsalane kwaye, ngokokutsho kwalo mfana, libhenela isenzo esithile. Kodwa emva koko wathetha into-into awathi kamva wayichaza kubahlobo bakhe njengeyona nto ilisikizi endakha ndayiva.
Wayelele apho, watsho, kwaye ekhulule iimpahla zakhe. Ke, ngentetho engacacanga ngokupheleleyo, wathi: 'Ndithathe ii-Ambien ezimbini, ke nantoni na oza kuyenza, kungcono uyenze ngaphambi kokuba ndife.' Uthe khange alale ubusuku kwiminyaka esixhenxe ngaphandle kwakhe Ambien.
Lo mfana wayeze ngobuso kunye nelungu le-Ambien Generation, apho kuvulwa khona kuthatha isihlalo sangasemva ukuze ukwazi ukucima. Kule edgy, post-9/11 sixeko, ukulala kubonakala ngakumbi njengelungelo elingenakuphikiswa: Ukujula kunye nokujika kwenzelwe iiswidi. Nangona i-Ambien, iyeza elithengisa kakhulu kweli lizwe, lihlala kwintengiso ukusukela ngonyaka we-1993, liya liqala ukuhlala kwindawo enye kubomi babaninzi baseNew York njengekofu necuba. Kwaye ukuba iViagra yayilichiza lase-boutique le-90's, ngoku abantu baseNew York bakhangela iziyobisi ezibenza bangabinaluncedo ngexesha lokulala. Isixeko esingaze silale siba sisixeko esingenakulinda ukuya kulala.
I-Ambien ibonakala ngathi iyaphepha nakuphi na ukubekwa ibala eluntwini. Ngexesha lokuxoxwa kwetyala elibandakanya umhleli weVogue u-Anna Wintour kunye nomongikazi wakhe wangaphambili ku-Okthobha ophelileyo, uncedo lwangaphambili olungenantlonelo lathi u-Ambien wayelichiza lokukhetha lika-Ms Wintour. Emuva ngo-Okthobha u-2003, ngoko-uNobhala welizwe u-Colin Powell waqhayisa ngentatheli yase-Saudi evela e-Asharq Al-Awsat yase London: Baliyeza elingummangaliso-hayi amayeza. Ungayibiza njani? Babizwa ngokuba yiAmbien, nto leyo intle kakhulu. Awusebenzisi Ambien? Wonke umntu apha usebenzisa i-Ambien. Umlingisi u-Scarlett Johannson uxelele i-InStyle ukuba yayiyintoni na into yokunyanga i-jet lag: Sela amanzi, thenga umqamelo wokuhamba wase-Brookstone, cela ugqirha wakho amayeza e-Ambien, kwaye uyakuphila. Kwiringi yesibini, uphawu lukaNaomi Watts londla umntwana wakhe ibhotolo yamandongomane kunye nesonka esine Ambien.
Ndifumana i-bang eyongezelelweyo yokulala kunye ne-Ambien kunokuba ndingenakho ngaphandle kwayo, utshilo ongxowankulu othe wathetha ngemeko yokungaziwa. Kodwa amaxesha ambalwa okuqala uyithatha, kufuneka ulumke. Qiniseka ukuba ulele, kuba ngokoqobo kwisithuba semizuzu emihlanu uyithathile, uya kudlula ngokoqobo naphina apho ukhoyo.
U-Liz Withers, usomashishini oneminyaka engama-28 ozimeleyo ohlala e-Upper East Side, uqikelela ukuba uthathe i-Ambien amatyeli ayi-100. Indinika obona buthongo busemnandi ebomini bam, utshilo. Ndiyithatha xa ndixinzelelekile emsebenzini, andikwazi ukulala, kuninzi engqondweni yam. Ndiyithatha lonto ndilale okosana. Uvele ulale ubuthongo obumnandi, kwaye xa uvuka kusasa, awuyiyo groggy. Kuyinto entle-andinakuphila ngaphandle kwayo…. Andizilibali izinto kusuku olulandelayo…. Ndiyithatha rhoqo.
Ukusetyenziswa kwemini ye-Ambien akuvakalanga. Ndinabaxhasi abaliqela, ekuphela kwendlela abafumana ngayo kwiiseshoni zokulamla okanye zokucebisa nabayeni babo nguAmbien, ligqwetha laseManhattan lokuqhawula umtshato. Bayazonkqonkqoza emva koko bazenzekelayo kwimizuzu engama-45. Nokuba yeyiphi na into enokuba khona kwizigulana, ilungile kwinkampani eyivelisayo.
Kunyaka ophelileyo, ukuthengiswa kwilizwe lonke kweAmbien kufikelele kwi-1.88 yezigidigidi zeedola. Ngegama layo lokukhohlisa-cinga ingxolo yokuma, ubumnandi obuhle, kusasa ekuseni (kusasa = kusasa, bien = okuhle) -I-Ambien ibonakala ngathi ibambelele kwintengiso. Kodwa linda: I-Sepracor's Lunesta, eyasungulwa kulenyanga ngephulo lesibhengezo se- $ 60 yezigidi, ithembisa ixesha elide, ukulala okungaphazamiseki, kwaye ayithwali isilumkiso se-Ambien sokuba umntu makayithathe kuphela iintsuku ezisixhenxe ukuya kwezili-10. Okwangoku, iSanofi-Aventis, abenzi beAmbien, balindele i-FD. imvume yenguqulo entsha ye-Ambien enokubangela ixesha lokulala ixesha elide.
Kwitheko lakutshanje, umdlali weqonga lomlingisi uHelen Hunt, umbhali wenoveli uMateyu Carnahan, ukhumbule ukulala kwakhe okubangelwe yi-Ambien: Unamaphupha angaqhelekanga. Ukuba uzama ukuhlala uphaphile, wenza iifowuni ongazikhumbuliyo-kufana nokuhlala kwindawo emnyama emnyama.
Kweli theko linye, u-Eric Gilliland, umbhali we-TV, uthe, Ambien wabusindisa ubomi bam ekuqaleni, kodwa kamva ndabuhlukumeza. Ndiwele imida yexesha ezisibhozo kwiintsuku ezintlanu kwaye ndoyisile. Ngoku ndithatha isithathu sepilisi kwaye kwanele.
Andikaze ndibenobuthongo ngaphandle kobusuku besibini eYurophu, emva koko ndithathe i-melatonin enye. Kodwa andizange ndilale, utshilo umbhali uErica Jong. Ndingalala phantse naphi na-kwinqwelomoya, kuloliwe. Ndiyolala. Ndingalala iiyure eziyi-14 ngobusuku kwaye ndonwabile. Andifuni Ambien. Ndiyathetha, thetha nam malunga ne-Effexor, i-anti-depressant: Ndiyayithanda loo nto.
Akunjalo njengokuba kwakumiselwe kum, watsho oneminyaka engama-28 ubudala osebenza ekushicileleni kwaye waqala ukuthatha i-Ambien ngexesha loxinzelelo lomtshato wakhe ozayo. Abahlobo bam abaninzi bebeyithatha kwaye bandinika ezinye, kwaye yeyona nto ifanelekileyo kobo busuku xa uvuke kade kwaye usebenza, kuba awudingi ukuba nexhala ngokuzibamba. Kukufumana nje ukuba ulale. Kuyakukhupha.
Asinguye wonke umntu ongumlandeli. Kumsitho wencwadi osandula ukubakho eManhattan, imvumi uJudy Collins uthe uthathe i-Ambien kube kanye. Kanye kunokwanele, utshilo. Andinakuze ndisondele kuyo. Sisiyobisi esoyikekayo, esoyikekayo. Ndinabantu abangena bevela ezindongeni. Ndibuyiselwe igxalaba kwiminyaka esixhenxe eyadlulayo-ibilolona tyando lukhulu, into enkulu, enkulu…. Ndithathe le pilisi, ndiyakuxelela, abantu bebephuma ezindongeni. Uyaphambana-uyadlala? Waphambana, woyika, woyika. Abaphambukeli ngokuqinisekileyo. Ndicinga ukuba enye yeengxaki kweli lizwe baninzi abantu abakuzo zombini okanye i-Ambien kunye neViagra. Ndiyathetha, ndinike ikhefu! I-Ambien iyingozi, ikhuthaza-ukusuka kwindawo yam yokujonga-imeko yengqondo. Ukuba unamava ngaphambili, ufuna ukuhlala kude nawo. Uyakwazo oko? Ukungabikho kokulala akuyi kukubulala. Ewe ndinobuthongo bokulala qho emva kwexesha-wonke umntu wenza. Ndiyavuka ndiyasebenza. Uyayazi into endincedayo? Ijusi encinci yeapile. Zininzi iindlela zokulala. Inye into yokulala apho kwaye uthandazele uxolo-ayisiyongcamango embi.
I-Ambien ikwiklasi yeziyobisi ezaziwa njengehypnotics. Xa uJacqueline Susann wayebhala i-Valley of the Dolls phakathi kwiminyaka engama-60, wakhankanya iipilisi zokulala njengeziphakathi koonodoli abancinci abagcina uNeely, uJennifer noAnne becazululwa njengoko bephila ubomi babo obumnandi basemva kwemfazwe esixekweni. Nangona kwakungoNeely, oonodoli bayeka ukusebenza: [S] waya egumbini lakhe lokulala, watsala iimfama… waginya iipilisi ezintlanu ezibomvu. Abahlanu ababomvu akukho nto bayenzileyo ngoku. Ngobusuku bokugqibela ebelala kuphela iiyure ezintathu enebomvu ezintlanu kunye namthubi amabini.
I-Ambien isebenza ngokwandisa iziphumo ze-neurotransmitter ebizwa ngokuba yi-GABA ekhuthaza ukulala. Amachiza ekujolise kuwo liqela elithile le-GABA receptors ngokuchasene noluhlu olubanzi, kwaye ke, ngokungafaniyo nokulala okudala, kunciphisa iziphumo ebezingalindelekanga ezinje ngokuba grogginess, ukulahleka kwememori, ukubona izinto ezingekhoyo kunye nokuqaqadeka. Kodwa i-Ambien isathathelwa ingqalelo njengokwenza umkhwa. Ulawulo loNyanzeliso lweziyobisi luchaza njengesiyobisi seShedyuli IV, okuthetha ukuba yinto elawulwayo enokubakho gadalala.
U-capitalist venture uthe uthathe i-Ambien qho ebusuku unyaka onesiqingatha. Emva kwethutyana iba nzima kakhulu, kodwa ufumana i-GABA ephezulu malunga nemizuzu engama-20 ngaphambi kokuba ulale, utshilo. Waqala ukumiselwa i-Ambien emva kokubandezeleka kwiveki yokulala ngexesha lohambo. Ndiphila ubomi obugeza ngokwenene, watsho. Ndikwinqwelomoya kakhulu. Ndinezivumelwano ezisixhenxe ezahlukeneyo ezenzeka ngexesha elinye. Inamandla-awuzange nanini na umzuzu.
Xa bexelelwa ukuba abantu basebenzisa i-Ambien ixesha elide kunexesha elimiselweyo, uMelissa Feltmann, osisithethi seSanofi-Aventis, wanyanzelisa ukuba i-Ambien ikhuselekile ukuyisebenzisa kangangeentsuku ezingama-30. Ileyibhile kwibhotile yamayeza ekufuneka ilinganiselwe kwiintsuku ezisixhenxe ukuya kwezili-10 ibhekisa kwii-hypnotics ngokubanzi, utshilo. I-Ambien ibonakalisiwe kunyango lwexeshana elifutshane lokungalali ngokwaneleyo kunikezelo lweentsuku ezingama-30. Uye wongeza, Ukuba abantu baya ngaphaya kwexesha elimiselweyo, ugqirha kunye nesigulana bathatha izigqibo malunga nonyango lwabo.
Ngokophando olwenziwe ngo-2005 yiNational Sleep Foundation, eMntla-mpuma weU.S., Iipesenti ezili-18 zabaphenduli zazifumana ukulala iiyure ezingaphantsi kwesithandathu ngobusuku bonke. Kodwa ngaba ukuvela kwipilisi sisicombululo?
Abantu abanakho ukuvula iingqondo zabo nokucima ngokungathi sinokucima isibane, utshilo uGqirha Daniel Salzman, ingcali yokulala kwiziko laseNew York Presbyterian Sleep / Wake Disorders Centre eWhite Plains. Siphila kuluntu-ngakumbi iNew York-apho sixakeke kakhulu. Ukukwazi ukwenza into akuthethi ukuba kufanelekile. Asizange sakhiwe kuluntu lweeyure ezingama-24.
Uye wongeza, Ngokutshintsha isingqisho se-circadian, indlela yakho yokulala yendalo, ngokuqinisekileyo uthatha umthwalo kwimpilo yakho.
UGqr.Salzman ukhuthaza iindlela zokuziphatha zokunyanga ukulala-ukulala kunye nezilumkiso malunga nokusetyenziswa gwenxa kwe Ambien. Inokuba yingxaki yokuba abantu bayithathe ngaphezulu kweeveki ezimbini, utshilo. Ngelixa unika umntu i-Ambien kwaye uphatha uphawu, bayakwazi ukulala kakuhle. Xa beyeka, oyena nobangela usekhona. Abantu abaninzi banokuphuhlisa ukuxhomekeka kwengqondo kwi-Ambien-okanye nakweyiphi na ipilisi yokulala, ngaloo nto. Ekugqibeleni baqala ukukholelwa ukuba abanakulala ngaphandle kwayo.
Ngokubanzi, abantu abaneengxaki zotywala bathanda ukuba neengxaki nge-benzos okanye i-Ambien, utshilo uGqirha Edward Kenny, ugqirha wengqondo ogqamile osebenza kwi-Upper West Side. Abantu abasebenzisa kakhulu i-Ambien bayisebenzisa ukumelana nobomi babo.
Ngokubhekisele kwiingozi ezinokubakho, ugqirha uKenny wongeze, Enye yezinto engakhange ifundwe, inokubangela ukutshintsha kwememori okufihlakeleyo. Akukho mntu ebefunda iziphumo zexesha elide ze-Ambien. Nge-benzos, ihippocampus inokuncipha.
Asazi ukuba kunokuba naziphi na iziphumo ezinobungozi, kodwa i-Ambien sisiyobisi esikhobokisayo esihlala sihleli, utshilo uGqirha Daniel Kripke, lelinye lamazwi ambalwa kwezobuchwephesha elineWebhusayithi, www.darksideofsleepingpills.com, elumkisa ingozi yemithi yokulala kagqirha. Kungathatha iminyaka eli-10 ukuya kwengama-20 ukwazi ukuba ziya kuba yintoni iziphumo zeli chiza. Kufana nendlela ushishino lwecuba olwalukho ngayo ngaphambi kokuba lulawulwe.
Akumangalisi ukuba, ezinye zezihlwele zedolophu zasebusuku ziye zabandakanyeka e-Ambien. Ibango kukuba xa umntu ethatha ezintathu okanye ezine i-Ambien aze azinyanzele ukuba ahlale ephaphile, kuya kubakho ukulandela izinto ezingekhoyo.
Ingaba umntu uthatha i-Ambien okanye cha, ngokuqinisekileyo ibe yinxalenye yento abantu baseNew York bathetha ngayo xa bethetha ngokulala.
Ndabekwa iipilisi zokulala ndineminyaka esi-8 ngugqirha wezifo zengqondo, utshilo umbhali uDaphne Merkin. Ambien ayilo thando lwam. Ndicinga ukuba i-Ambien isebenza kwii-insomniacs ezingafiyo. Ndizamile izolo ebusuku; Ndayithatha ngeKlonopin. Ndicinga ukuba ukuphuthelwa kuya kwinqanaba ukuya kwimeko engapheliyo ye-melancholia…. Njengokuba ndinengxaki yokuvuka, ndinengxaki yokulungisa. Ukudityaniswa kokudityaniswa kwe Ambien kukuba isebenza ngokukhawuleza kwaye iphume kuwe ngokukhawuleza. Kodwa ndinokungakhuseleki kakhulu. Andiyi kuzibiza ngokuba yi-junkie, kuba nayiphi na imikhwa ye-junkie ibethelwe ngaphandle kwam ukususela ebuntwaneni bam. Ndicinga ukuba i-Ambien sisiyobisi esihle kakhulu; khange nje isebenze kum. Zange khe ndizame nakwifomu yeemiligram ezintlanu-ndaya ngqo kwii-milligram ezili-10 naseKlonopin, kwaye ndandisendivukile iyure enesiqingatha kamva…. Mva nje bendizama ukungaseli iipilisi zokulala…. Xanax andifumani mkhulu; IKlonopin yiValium entsha. Ndakhe ndathunyelwa ekunciphiseni owathi kum ukuba andivelanga kwimvelaphi yobu-Orthodox, bendiya kuba likhoboka le-heroin, apho ndicinga ukuba wayethetha ukuba ndifuna ukuphazamisa iimvakalelo zam. Ngokusisiseko, kwinqanaba elithile ndifuna ukudibanisa…. Uhlobo oluthile lweTV luyenzela mna: Ukwabelana ngesondo kunye neSixeko. Ndiba nohlobo lokuzibandakanya ngokufanelekileyo kweziphi izihlangu aza kuzikhupha…. UCharlie Rose? Hayi, uyandicaphukisa.
Abantu, ngakumbi kwindawo yemidlalo yeqonga, sinengxaki enkulu yokulala, utshilo umlingisi uAdrian Zmed weT.J. Hooker udumo. Ingqondo yethu-asinakuyicima. Ndikhe ndabona Ambien. Ndiye ndayijonga kwaye ndithe, Hmmmm. Ndisebenza kwindawo yokubonela, andikwazi ukuyivala kude kube ngu-2, 3 kusasa; ingqondo nje ayiyi kuyeka. Ndiza kuzama nantoni na. Ndizamile yonke into onokuyicinga. Ngamanye amaxesha uhlala nje de ulale. Ndisebenzisa iiplagi zendlebe-ndizivalele umhlaba-kwaye mhlawumbi iziselo ezimbalwa ngaphambi kokuba ndilale ndize ndizishiye ngelo xesha.
Kwaye, u-Ambien uwela kudidi lwe-pragmatic pharmacology, utshilo uJeremy Walker, kaJeremy Walker kunye no-Associates, inkampani yokwazisa ngemovie. Ukuba unentloko ebuhlungu, thatha iasprini. Ujonge oomama abaphelelwe lithemba kwaye nonke ninenxeba emva koko-ndiye ndizibone ndithatha isiqingatha se-Ambien ngeCawa ebusuku, ngenxa yoko uphele iveki yonke ungafakwanga.
Ekuqaleni, isizathu sokuba ndifumane amayeza kukuba kwakungunyaka ongaphambili, kwiSundance Film Festival, ndandikhe ndilale ngenxa yoxinzelelo, waqhubeka. Ndacela ugqirha wam amayeza kunyaka olandelayo, kwaye nangasiphi na isizathu andikaze ndisebenzise. Emva koko ndabona ingxaki yangeCawa-ngokuhlwa.
Into ehlekisayo nge-Ambien yile, uyazi xa uyozela-ngokwendalo uyozela-amehlo akho ayadinwa, kwaye afike omile kwaye uwahlikihle, kwaye luhlobo lwesandulela sokulala, wongeze uMnu Walker. Ndiqaphele ukuba yenye yezinto ezenziwa yi-Ambien: Amehlo akho ayoma, uwaphulula kwaye ufumana into encinci, emva koko ufuna ukulala. Kwaye iyenza ngemizuzu.
Kodwa kukho umbuzo oshiyekileyo uxhonyiwe: Ngaba kusempilweni ngenene ukuba ungaze ube nobusuku obumnyama bomphefumlo, ezo zinto zoyikekayo zokwehla kwezihlwitha ezihlala zikhokelela kwimpefumlelo kunye nentlonipho ethobekileyo kwiimfihlakalo zentliziyo yomntu?
I-Ambien iyasebenza ngokufutshane, kodwa uye wafumanisa oyena nobangela, utshilo uGqirha Salzman. Kutheni le nto abantu befuna ukuthatha ipilisi ukuze balale ubomi babo bonke?
Ingxelo eyongezelelweyo nguGeorge Gurley, uRebecca Dana kunye noRaquel Hecker.
