Iirhafu zokuSebenza ngokuSebenzayo kwiHlabathi lazo zonke i-COVID-19 Vaccine, esekwe kubudala kunye neMpawu

UModerna, uJohnson noJohnson kunye noPfizer (ngoncedo lwe-BioNTech yaseJamani) baphuhlise amayeza amathathu asebenza kakhulu e-COVID-19 ngexesha lokurekhoda phantsi kongxamiseko lobhubhane we-coronavirus.

Aba benzi bamachiza baxela kuphela amanqanaba okusebenza ngokuchanekileyo kwezitofu zabo xa behambisa idatha yolingo kwi-FDA yokufumana isigunyaziso sokusetyenziswa okungxamisekileyo. Kodwa njengoko izigidi zokudubula ziqengqeleka ezibhedlele nasezikliniki kwaye zingena ezingalweni zabantu, idatha ethe yafumaneka kwaye yavumela izazinzulu ukuba zivavanye ifuthe lezitofu zokugonya kumaqela athile abantu. Abaphuhlisi bezitofu ezivunyiweyo bebeqhuba nezifundo ekujoliswe kuzo ngakumbi ukujongana notshintsho lwentsholongwane kunye nokwenza isibhamu esele sikhona kufumaneke kubemi abaninzi.

NgoLwesithathu, iPfizer kunye neBioNTech utshilo Idatha entsha yesilingo se-3 yolingo ibonakalisile ukuba isitofu sokugonya se-mRNA-based COVID-19 BNT162b2 sisebenza ngepesenti eyi-100 kwaye siyanyamezeleka kulutsha oluneminyaka eli-12 ukuya kweli-15.

Iinkampani ziceba ukungenisa iziphumo kwi-FDA ngokukhawuleza ukuze kwandiswe isigunyaziso sokusetyenziswa okungxamisekileyo ngethemba ngaphambi kokuqala konyaka wesikolo olandelayo. Isitofu sokugonya ngoku sigunyazisiwe ukuba sisetyenziswe ngokungxamisekileyo kubantu abaneminyaka eli-16 nangaphezulu eMelika.

Idatha entsha kaPfizer ayikaphononongwa ngoontanga. Uvavanyo lwesigaba sesi-3 lubhalise abantwana abakwishumi elivisayo abangama-2,260 abaneminyaka eli-12 ukuya kweli-15 ngokulinganayo besahlulahlula iqela lokugonya kunye neqela le-placebo. Emva kweedosi ezimbini, iimeko ze-18 ze-COVID-19 zaqwalaselwa kwiqela le-placebo kuthelekiswa nelinye kwiqela eligonyweyo.

UModerna wenza iimvavanyo ezifanayo kulutsha nakubantwana. Inkampani inezilingo ezibini eziqhubekayo: omnye wabantwana abaneminyaka eli-12 ukuya kweli-17 kwaye omnye wabo uneminyaka emi-6 ukuya kwiminyaka elishumi elinanye. I-EUA eyandisiweyo yabantwana abadala kuneminyaka eyi-12 inokufumaneka ngoJulayi okanye ngo-Agasti, uqikelela uBuddy Creech, umlawuli weVanderbilt University's Vaccine Research Programme kunye nomphenyi kwizilingo zabantwana zikaModerna, kwi-CNN nganye . Abantwana abancinci kuya kufuneka balinde de kube nguNovemba okanye ngoDisemba.

Apha ngezantsi siqokelele amanqanaba okusebenza kokugqibela kwezitofu ezintathu ezigunyazisiweyo e-U.S-Pfizer, BioNTech kunye noJohnson & Johnson-esekwe kulingo kunye nedatha yokwenyani yelizwe.

IPfizer-BioNTech: Ngokubanzi iipesenti ezingama-94 ziyasebenza

• Ngokweqela Leminyaka:

100% kubantu abaneminyaka eli-12 ukuya kweli-15 ubudala;

Iipesenti ezingama-95 zabantu ubudala 16 nangaphezulu;

Iipesenti ezingama-94 zabantu abaneminyaka engama-65 nangaphezulu;

Iipesenti ezingama-61 zabantu 70 nangaphezulu;

Iipesenti ezingama-70 zabantu abaneminyaka engama-80 nangaphezulu.

• Ngu Iimpawu :

I-94% iyasebenza ekuthinteleni ukusuleleka kwezifo;

I-97% iyasebenza xa usuleleko luphawu, iimeko ezinzima kunye nokufa.

Okwangoku: Ngokubanzi i-94.5% iyasebenza

• Ngokweqela Leminyaka:

95.6% kubantu abaneminyaka eli-18 ukuya kuma-65 ubudala;

I-86.4% yabantu ngaphezulu kweminyaka engama-65.

• Ngu Iimpawu:

I-94.1% isebenzayo ekukhuseleni ukusuleleka kwempawu;

I-100% isebenza kakuhle kwiimeko ezinzima.

UJohnson noJohnson: Ngokubanzi i-66% iyasebenza (i-74.4% e-US)

• Ngu Iqela lobudala:

I-66.1% yabantu abaneminyaka eyi-18 ukuya kwi-59;

I-66.2% yabantu abadala kunye nama-60.

• Ngeempawu:

I-66% iyasebenza ekuthinteleni ukusuleleka kwempawu;

I-85% esebenzayo kwiimeko ezinzima;

100% esebenzayo ekuthinteleni ukulaliswa esibhedlele nasekufeni.

Phawula: Zonke izitofu ezivunyiweyo zikulungele ukusetyenziswa ngobuninzi kwaye akukho sizathu sokwenza iyeza lokugonya elinye ngaphezulu kwelinye.